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簡(jiǎn)要描述：This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
產(chǎn)品型號(hào)：bsm-61145R廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2025-03-02訪 問 量： 122產(chǎn)品分類
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